The 1964 Portsmouth Trojans posted an 18-5 record en route to a Class AA district championship. Larry Hisle and Al Oliver were the two leading scorers on this team, which had some notable wins along the way. The Trojans opened the season with wins over Columbus Grandview and Hillsboro, and then added a win over Lancaster. PHS beat Middletown at Grant Gym 69-67 in 3 OT, and the Men of Troy also knocked off highly touted Huntington WV 82-79 in OT. The Trojans destroyed Chillicothe 95-59, and bested Ironton twice. Dayton Belmont came into Portsmouth and fought off a scrappy Trojan squad 79-60. Belmont featured future NBA players Bill Hosket and Don May, and the Bison would go on to win the 1964 Class AA state title.
The Greyhounds of Grove City would end the Trojans season with a win in the regional semifinals. The district championship was the 4th in 5 years for Portsmouth in Class AA. The 1964 season would be the last for the Trojans in Grant Gym, as they would move into the then brand new 8th street gym for the 1964-65 season.